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IMMUNOGLOBULIN VS THEIR TYPES, EXAMPLE

 IMMUNOGLOBULIN VS THEIR TYPES, EXAMPLE

1.IgG-

*IgG antibodies are very important in fighting bacterial and viral infections.

*it is large in number 

*it can pass through the placenta 

*Normal Ranges Adult: IgG 6.0 - 16.0g/L

*Example - it is found in all body fluids, present in blood and tissue fluids 


2.IgM - 

It is the largest antibody, and it is the first antibody to appear in the response to initial exposure to an antigen. 

*it is large in size 

*Normal Ranges of IgM 0.4 - 2.5g/L.

*example - in blood and lymph fluid 


3.IgA - 

*it is an antibody that plays a crucial role in the immune function of mucous membranes.

*it is the first line of defence in the resistance against infection, via inhibiting bacterial and viral adhesion to epithelial cells and by neutralisation of bacterial toxins and virus, both extra- and intracellularly

*Normal Ranges - 80 – 350 mg/dL

*Example - 

IgA is found in mucous membranes, especially in the respiratory and digestive tracts. It is also found in saliva, tears, and breast milk


 4.IgD-

a monomeric antibody isotype that is expressed in the plasma membranes of immature B-lymphocytes.

*it helps in differentiation of B lymphocytes 

*Normal Ranges 0.2-121 mg/liter

*Example - found in small amounts in blood serum

5.IgE-

IT is a type of antibody that has been found only in mammals

*if you have an allergy, your immune system overreacts to an allergen by producing antibodies called Immunoglobulin E (IgE)

*it is found in hypersensitivity or allergic reaction 

*Normal Ranges - 150 to 1,000 UI/ml

*Example - found in the lungs, skin, and mucous membranes.



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